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We show that for a large class of knots and links with complements in
S3 admitting a hyperbolic structure, we can determine bounds on the
volume of the link complement from combinatorial information given by
a link diagram. Specifically, there is a universal constant C such
that if a knot or link admits a prime, twist reduced diagram with at
least 2 twist regions and at least C crossings per twist region, then
the link complement is hyperbolic with volume bounded below by 3.3515
times the number of twist regions in the diagram. C is at most 113.
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